• Opuntia (Linnaeus) P. Miller, 1754 [Family: Cactaceae]
• Opuntia F. Naccari, 1828 (unaccepted) [Family: Udoteaceae]
• Opuntia abjecta Small accepted as Opuntia triacantha (Willd.) Sweet
• Opuntia acanthocarpa Engelm. & Bigelow
• Opuntia aggeria B.E. Ralston & Hilsenbeck
• Opuntia ammophila Small accepted as Opuntia humifusa (Raf.) Raf.
• Opuntia antillana Britt. & Rose accepted as Opuntia cubensis Britt. & Rose
• Opuntia arborescens Engelm. accepted as Opuntia imbricata (Haw.) DC.
• Opuntia arbuscula Engelm.
• Opuntia arenaria Engelm.
• Opuntia arizonica Griffiths accepted as Opuntia phaeacantha Engelm.
• Opuntia atrispina Griffiths
• Opuntia atrocapensis Small accepted as Opuntia stricta (Haworth) Haworth, 1812
• Opuntia aurantiaca Lindl.
• Opuntia aurea E.M. Baxter
• Opuntia aureispina (Brack & Heil) Pinkava & Parfitt
• Opuntia austrina Small accepted as Opuntia humifusa (Raf.) Raf.
• Opuntia ballii Rose accepted as Opuntia macrorhiza Engelm.
• Opuntia barkleyana (Daston) Rowley accepted as Opuntia pulchella Engelm.
• Opuntia basilaris Engelm. & Bigelow
• Opuntia bentonii Griffiths accepted as Opuntia stricta (Haworth) Haworth, 1812
• Opuntia bigelovii Engelm.
• Opuntia boringuensis Britton & Rose
• Opuntia borinquensis Britt. & Rose
• Opuntia brachyarthra Engelm. & Bigelow accepted as Opuntia fragilis (Nutt.) Haw.
• Opuntia brachyclada Griffiths accepted as Opuntia basilaris Engelm. & Bigelow
• Opuntia brachyrhopalica (Daston) Rowley accepted as Opuntia pulchella Engelm.
• Opuntia brasiliensis (Willd.) Haw.
• Opuntia calcicola Wherry accepted as Opuntia humifusa (Raf.) Raf.
• Opuntia californica (Torr. & Gray) Coville
• Opuntia californica Engelm. accepted as Opuntia tetracantha Toumey
• Opuntia camanchica Engelm. & Bigelow accepted as Opuntia phaeacantha Engelm.
• Opuntia canada Griffiths accepted as Opuntia phaeacantha Engelm.
• Opuntia cantabrigiensis Lynch
• Opuntia chihuahuensis Rose
• Opuntia chisosensis (Anthony) Ferguson
• Opuntia chlorotica Engelm. & Bigelow
• Opuntia clavata Engelm.
• Opuntia cochenillifera (L.) P. Mill.
• Opuntia columbiana Griffiths accepted as Opuntia erinacea Engelm. & Bigelow ex Engelm.
• Opuntia compressa auct. non J.F. Macbr. accepted as Opuntia humifusa (Raf.) Raf.
• Opuntia compressa J.F. Macbr. accepted as Opuntia ficus-indica (L.) P. Mill.
• Opuntia congesta Griffiths
• Opuntia cordobensis Speg.
• Opuntia cordodensis Speg.
• Opuntia covillei Britt. & Rose accepted as Opuntia littoralis (Engelm.) Cockerell
• Opuntia cubensis Britt. & Rose
• Opuntia cumulicola Small accepted as Opuntia humifusa (Raf.) Raf.
• Opuntia curvospina Griffiths
• Opuntia cymochila Engelm. & Bigelow
• Opuntia davisii Engelm. & Bigelow accepted as Opuntia tunicata (Lehm.) Link & Otto
• Opuntia demissa Griffiths
• Opuntia densispina B.E. Ralston & R.A. Hilsenbeck
• Opuntia deserta Griffiths
• Opuntia dillei Griffiths accepted as Opuntia engelmannii Salm-Dyck
• Opuntia dillenii (Ker-Gawl.) Haw. accepted as Opuntia stricta (Haworth) Haworth, 1812
• Opuntia discata Griffiths
• Opuntia drummondii Graham accepted as Opuntia pusilla (Haw.) Nutt.
• Opuntia dulcis Engelm. accepted as Opuntia phaeacantha Engelm.
• Opuntia eburnispina Small accepted as Opuntia humifusa (Raf.) Raf.
• Opuntia echinocarpa Engelm. & Bigelow
• Opuntia edwardsii V. & K. Grant
• Opuntia ellisiana Griffiths
• Opuntia emoryi auct. non Engelm. accepted as Opuntia parishii Orcutt
• Opuntia emoryi Engelm. accepted as Opuntia kunzei Rose
• Opuntia engelmannii Salm-Dyck
• Opuntia erinacea Engelm. & Bigelow ex Engelm.
• Opuntia ficus-indica (L.) P. Mill.
• Opuntia flexospina Griffiths accepted as Opuntia engelmannii Salm-Dyck
• Opuntia fosbergii C.B. Wolf
• Opuntia fragilis (Nutt.) Haw.
• Opuntia fulgida Engelm.
• Opuntia ganderi (C.B. Wolf) J. Rebman & Pinkava
• Opuntia gilvescens Griffiths accepted as Opuntia phaeacantha Engelm.
• Opuntia gosseliniana A. Weber
• Opuntia gracilicylindrica (Wieg. & Backeberg) Rowley accepted as Opuntia pulchella Engelm.
• Opuntia grahami
• Opuntia grahamii Engelm.
• Opuntia grandiflora Engelm. accepted as Opuntia macrorhiza Engelm.
• Opuntia heacockiae Arp
• Opuntia humifusa (Raf.) Raf.
• Opuntia hystricina Engelm. & Bigelow accepted as Opuntia erinacea Engelm. & Bigelow ex Engelm.
• Opuntia imbricata (Haw.) DC.
• Opuntia impedata Small accepted as Opuntia humifusa (Raf.) Raf.
• Opuntia juniperina Britt. & Rose accepted as Opuntia polyacantha Haw.
• Opuntia kelvinensis V. & K. Grant
• Opuntia kleiniae DC.
• Opuntia kunzei Rose
• Opuntia laevis Coult. accepted as Opuntia phaeacantha Engelm.
• Opuntia lata Small accepted as Opuntia humifusa (Raf.) Raf.
• Opuntia leptocarpa MacKensen accepted as Opuntia macrorhiza Engelm.
• Opuntia leptocaulis DC.
• Opuntia leucotricha DC.
• Opuntia lindheimeri Engelm. accepted as Opuntia engelmannii Salm-Dyck
• Opuntia linguiformis Griffiths accepted as Opuntia engelmannii Salm-Dyck
• Opuntia littoralis (Engelm.) Cockerell
• Opuntia longiareolata Clover & Jotter accepted as Opuntia basilaris Engelm. & Bigelow
• Opuntia mackensenii Rose accepted as Opuntia macrorhiza Engelm.
• Opuntia macrantha Gibbes accepted as Opuntia stricta (Haworth) Haworth, 1812
• Opuntia macrocentra Engelm.