• Sarapus Fischer de Waldheim, 1821 accepted as Sphaerites Duftschmid, 1805 [Family: Sphaeritidae]
• Sarapus Schönherr, 1826 accepted as Brachonyx Schönherr, 1825 [Family: Curculionidae]
• Sarapus Villa & Villa, 1833 accepted as Ellescus Dejean, 1821 [Family: Curculionidae]
• Sarapus Walker, 1855 accepted as Asparus Watson in Watson, Fletcher & Nye, 1980 [Family: Erebidae]
• Scapus Norman, 1875 (uncertain)
• Sciapus Zeller, 1842
• Scirpus Linnaeus, 1753
• Scopus A.K. Benecke, 1976 † (uncertain) [Family: Dictyopteridiales (awaiting allocation)]
• Scopus Brisson, 1760 [Family: Scopidae]
• Scopus Oken, 1817 (unaccepted) [Family: Aves (awaiting allocation)]
• Scopus Scudder, 1882 (unaccepted > nomen nudum) [Family: Mollusca (awaiting allocation)]
• Scopus Sellards, 1907 † accepted as Protereisma Sellards, 1907 † [Family: Protereismatidae]
• Scrupus Finlay, 1926
• Sirpus Gordon, 1953
• Strepus Cheng, Liu & Dai, 2016
• Styripus Rafinesque, 1814 (uncertain)