• Sinisus Heude, 1892 accepted as Sus Linnaeus, 1758
• Spilotus Leconte, 1862
• Spinacus Keifer, 1979
• Spinatus Dekkers, Liverani, Ćorić, Maxwell & Landau, 2020 †
• Spinilus Blackwelder, 1942 accepted as Lispinus Erichson, 1840
• Spinodus Dzik, 1976 †
• Spinops Farke, Ryan, Barrett, Tanke, Braman, Loewen & Graham, 2011 †
• Spinopsis Orlov, 1990 † (uncertain)
• Spinosodus Breuning & de Jong, 1941
• Spinus Guichenot in Gay, 1849 accepted as Etmopterus Rafinesque, 1810 [Family: Etmopteridae]
• Spinus Hong, 1982 † (uncertain) [Family: Hemiptera (awaiting allocation)]
• Spinus Koch, 1816 accepted as Carduelis Brisson, 1760 [Family: Fringillidae]
• Spinus Möhring, 1758 accepted as Carduelis Brisson, 1760 [Family: Fringillidae]
• Spirodus Kade, 1858 (uncertain)
• Stenosus Chamberlin, 1949 (uncertain)