Agoutis Gray, 1821 accepted as Cuniculus Brisson, 1762 (original description)
Ancyllus Gray, 1821 accepted as Ancylus O. F. Müller, 1773 (original description)
Babiroussus Gray, 1821 accepted as Babyrousa Perry, 1811 (original description)
Calamara Gray, 1821 (original description)
Calogenus Gray, 1821 † accepted as Cuniculus Brisson, 1762 (original description)
Canna Gray, 1821 (original description)
Catablepas Gray, 1821 accepted as Connochaetes Lichtenstein, 1814 (original description)
Coendore Gray, 1821 † accepted as Coendou Lacepède, 1799 (original description)
Coesiodes Gray, 1821 accepted as Phalanger Storr, 1780 (original description)
Criopus Gray, 1821 (original description)
Crytoplax Gray, 1821 accepted as Cryptoplax Blainville, 1818 (original description)
Cyclopes Gray, 1821 (original description)
Cymbula Gray, 1821 accepted as Cymbulia Péron & Lesueur, 1810 (original description)
Delphinaster Gray, 1821 accepted as Delphinapterus Lacépède, 1804 (original description)
Dipsus Gray, 1821 accepted as Dipus Zimmermann, 1780 (original description)
Dugongidus Gray, 1821 accepted as Dugong Lacépède, 1799 (original description)
Georyclus Gray, 1821 accepted as Georychus Illiger, 1811 (original description)
Gerbellus Gray, 1821 accepted as Gerbillus Desmarest, 1804 (original description)
Getulus Gray, 1821 (original description)
Hanno Gray, 1821 accepted as Nasalis Geoffroy, 1812 (original description)
Hydrochoenus Gray, 1821 accepted as Hydrochoerus Brisson, 1762 (original description)
Hyperdordons Gray, 1821 accepted as Hyperoodon Lacépède, 1804 (original description)
Imarginula Gray, 1821 accepted as Emarginula Lamarck, 1801 (original description)
Kola Gray, 1821 accepted as Phascolarctos Blainville, 1816 (original description)
Laminaria Gray, 1821 (original description)
Laratus Gray, 1821 accepted as Hylobates Illiger, 1811 (original description)
Mephritis Gray, 1821 accepted as Mephitis Geoffroy & Cuvier, 1795 (original description)
Mimeles Gray, 1821 accepted as Pan Oken, 1816 (original description)
Mitrula Gray, 1821 (original description)
Myale Gray, 1821 accepted as Desmana Güldenstädt, 1777 (original description)
Navicellus Gray, 1821 (original description)
Nyctimones Gray, 1821 (original description)
Nylgau Gray, 1821 (original description)
Onyx Gray, 1821 accepted as Oryx Blainville, 1816 (original description)
Otcarus Gray, 1821 (original description)
Paphio Gray, 1821 accepted as Mandrillus Ritgen, 1824 (original description)
Pecotus Gray, 1821 (original description)
Phacochaeres Gray, 1821 accepted as Phacochoerus F. Cuvier, 1826 (original description)
Phocena Gray, 1821 accepted as Phocoena G. Cuvier, 1816 (original description)
Phytia Gray, 1821 accepted as Pythia Röding, 1798 (original description)
Plectophorus Gray, 1821 (original description)
Potorus Gray, 1821 accepted as Potorous Desmarest, 1804 (original description)
Psammolia Gray, 1821 accepted as Psammobia Lamarck, 1818 accepted as Gari Schumacher, 1817 (original description)
Rabienus Gray, 1821 accepted as Tarsius Storr, 1780 (original description)
Rattus Gray, 1821 accepted as Rattus Fischer de Waldheim, 1803 (original description)
Rhynolophus Gray, 1821 accepted as Rhinolophus Lacepède, 1799 (original description)
Rotaclea Gray, 1821 (original description)
Rousettus Gray, 1821 (original description)
Scyllea Gray, 1821 accepted as Scyllaea Linnaeus, 1758 (original description)
Septarius Gray, 1821 † accepted as Septaria Férussac, 1807 (original description)
Spherula Gray, 1821 (original description)
Stomata Gray, 1821 accepted as Stomatia Helbling, 1779 (original description)
Unaus Gray, 1821 (original description)
Unaüs Gray, 1821 accepted as Unaus Gray, 1821 (original description)
Vulpis Gray, 1821 accepted as Vulpes Frisch, 1775 (original description)